The aim of this study was to describe the extent and yield of daily clinical practice when staging patients with a locoregional recurrence (LRR) of breast carcinoma and to explore the prospects for positron emission tomography (PET). The population-based Eindhoven Cancer Registry was used to select all breast cancer patients in the southeast of the Netherlands with a first episode of LRR between January 1, 1994 and June 30, 2000 (n=175). Additional data concerning staging procedures and follow-up were collected from the medical records. Furthermore, we asked 77 physicians (response: 75%) about their opinions on staging procedures and actual treatment policy. At LRR presentation, 16% of patients were found to have distant metastases. An additional 24% were diagnosed with distant metastases within 18 months. The questionnaire revealed that 33% of clinicians thought that the sensitivity of conventional imaging techniques was too low. We tend to conclude that in daily clinical practice there is a need for more sensitive dissemination tests for patients with a LRR of breast cancer.

2-Fluoro-2-deoxy-D-glucose, Breast cancer, PET, Positron emission tomography, Recurrence, Staging
dx.doi.org/10.1016/j.ejca.2004.03.012, hdl.handle.net/1765/63091
European Journal of Cancer
Erasmus MC: University Medical Center Rotterdam

van Oost, F.J, van der Hoeven, J, Hoekstra, O.S, Voogd, A.C, Coebergh, J.W.W, & van de Poll-Franse, L.V. (2004). Staging in patients with locoregionally recurrent breast cancer: Current practice and prospects for positron emission tomography. European Journal of Cancer, 40(10), 1545–1553. doi:10.1016/j.ejca.2004.03.012