Diversion colitis is an inflammatory process occurring in segments of the colorectum surgically diverted from the fecal stream. Clinical symptoms of this condition are rectal discomfort, pain, discharge, and bleeding. We diverted isolated segments of sigmoid to create neovaginas in patients with aplasia vaginae and in male to female transsexuals. In contrast to what is reported in most studies of diversion colitis, the neovagina consists of an isolated segment not connected to the anus in patients without any pre-existing bowel disease. To investigate the occurrence of diversion colitis in these sigmoid-neovaginas we studied biopsy specimens from 13 patients. Most of the patients complained of discharge and slight blood loss from their sigmoid-neovagina. Microscopic examination of the biopsy specimens showed lymphocytic infiltration in all cases. Four cases showed an acute inflammatory infiltrate in the lamina propria. Our results indicate that the changes observed on clinical and histopathologic examinations represent the entity of mild diversion colitis. We conclude that diversion colitis also occurs in a sigmoid neovagina.

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doi.org/10.1016/0046-8177(93)90134-3, hdl.handle.net/1765/63159
Human Pathology
Department of Gynaecology & Obstetrics

Toolenaar, T.A, Freundt, I, Huikeshoven, F.J, Drogendijk, A.C, Jeekel, J, & Chadha-Ajwani, S. (1993). The occurrence of diversion colitis in patients with a sigmoid neovagina. Human Pathology, 24(8), 846–849. doi:10.1016/0046-8177(93)90134-3