Hidradenitis suppurativa (HS) is a chronic of recurrent, inflammatory, follicular disease that usually presents after puberty with painful deep-seated, inflamed lesions in the inverse skin areas of the body. It has been hypothesized that mechanical pressure or friction is a risk factor for HS. We describe the case of a man with a lower leg amputation who presented HS-like lesions on his leg stump after wearing a leg prosthesis. Although pilonidal sinus-like disease could not be excluded, we diagnosed him with HS-like lesions, induced by prosthesis-related friction. We argue that this case supports the concept that mechanical friction and a warm humid microclimate by occlusion contribute to HS development.

Acne inversa, Friction, Hidradenitis suppurativa, Leg stump, Prosthesis
dx.doi.org/10.1111/j.1600-0625.2012.01443.x, hdl.handle.net/1765/63622
Experimental Dermatology
Department of Dermatology

de Winter, K, van der Zee, H.H, & Prens, E.P. (2012). Is mechanical stress an important pathogenic factor in hidradenitis suppurativa?. Experimental Dermatology, 21(3), 176–177. doi:10.1111/j.1600-0625.2012.01443.x