2001-08-29
Papillary necrosis associated with the HIV protease inhibitor indinavir
Publication
Publication
Infection: journal of infectious disease , Volume 29 - Issue 4 p. 232- 233
The HIV protease inhibitor indinavir may cause nephrolithiasis and interstitial nephritis. The renal consequences of indinavir-associated nephrotoxicity are uncertain. We report a case of papillary necrosis in a patient treated with indinavir. An asymptomatic HIV-infected woman experienced right-sided renal colicky pain during treatment with indinavir. She passed a non-solid stone and continued indinavir treatment. Intravenous pyelogram performed 20 months later following an episode of left-sided colicky pain showed right-sided papillary necrosis. Indinavir-associated nephrolithiasis and chronic interstitial nephritis were the only possible causes identified in this patient. Physicians should be aware that indinavir nephrolithiasis may cause papillary necrosis.
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doi.org/10.1007/s15010-001-1105-y, hdl.handle.net/1765/63965 | |
Infection: journal of infectious disease | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Dieleman, J., van der Feltz, M., Bangma, C., Stricker, B., & van der Ende, M. (2001). Papillary necrosis associated with the HIV protease inhibitor indinavir. Infection: journal of infectious disease, 29(4), 232–233. doi:10.1007/s15010-001-1105-y |