Pneumoperitoneum, as used in laparoscopic donor nephrectomy (LDN), may result in negative effects on renal function in donor and recipient. This study compares long-term serum creatinine in donor and recipient after laparoscopic and open donor nephrectomy (ODN). A retrospective analysis of 120 LDN and 100 ODN donors and their recipients was performed. Serum creatinine of donor and recipient was recorded and analyzed. The follow-up period posttransplantation was 3 years. Serum creatinine in the recipients was significantly higher in the LDN groups the first week after transplantation. Serum creatinine in the donor was significantly higher in the LDN group at 1 day, 3 months, and 1 year posttransplant. Finally, creatinine levels remained 40% higher compared to preoperative values in both donor groups. LDN results in higher short-term serum creatinine levels in donor and recipient. Long-term serum creatinine levels were comparable after LDN or ODN in donor and recipient. Copyright

Donor, Laparoscopy, Recipient, Renal function
dx.doi.org/10.1097/01.tp.0000172219.10178.0d, hdl.handle.net/1765/64693
Transplantation
Department of Surgery

Smits-Lind, M.Y, Mertens Zur Borg, I.R.A.M, Hazebroek, E.J, Hop, W.C.J, Alwayn, I.P.J, Weimar, W, & IJzermans, J.N.M. (2005). The effect of laparoscopic and open donor nephrectomy on the long-term renal function in donor and recipient: A retrospective study. Transplantation, 80(5), 700–703. doi:10.1097/01.tp.0000172219.10178.0d