Plaque volume determined by common linear 3-D IVUS analysis systems will show under- or overestimation in curved vessel segments because these systems approximate the true 3-D transducer pull-back trajectory by a straight line. We developed a mathematical model that showed that the error is primarily dependent on the curvature of the pull-back trajectory and not on vessel tortuosity. Furthermore, we measured this error in vivo in the coronary arteries of 15 patients, comparing the plaque volume using a true 3-D reconstruction method with that of the linear approach. The in vivo plaque volume error ranged from 2.3% to -1.2% for 15 coronary segments with lengths ranging from 38.8 to 89.1 mm (62.2 ± 13 mm). The volume error introduced by linear 3-D IVUS analysis systems is dependent on the curvature of the pull-back trajectory. The error measured in vivo was small and inversely related to segment length. Copyright

Curvature, IVUS, Plaque, Volume error,
Ultrasound in Medicine & Biology
Department of Cardiology

Schuurbiers, J.C.H, von Birgelen, C, Wentzel, J.J, Bom, N, Serruys, P.W.J.C, de Feyter, P.J, & Slager, C.J. (2000). On the IVUS plaque volume error in coronary arteries when neglecting curvature. Ultrasound in Medicine & Biology, 26(9), 1403–1411. doi:10.1016/S0301-5629(00)00295-7