Churg-Strauss syndrome is an uncommon multisystem disorder characterized by asthma, eosinophilia and vasculitis. We report on a 12-year-old boy with asthma and deterioration of his general condition, who was eventually diagnosed with an ANCA-negative Churg-Strauss syndrome. The propositus included, 50 cases of childhood Churg-Strauss syndrome have been reported. The patient characteristics and clinical characteristics of these children are summarized. The respiratory tract is most frequently involved with pulmonary infiltrates, asthma and sinusitis. Early recognition of childhood Churg-Strauss syndrome is important as delayed diagnosis can lead to severe organ involvement, and possible fatal outcome.

Asthma, Child, Churg-Strauss syndrome, Eosinophilia, Eosinophilic lung disease, Pulmonary infiltrate, Vasculitis
dx.doi.org/10.1016/j.rmcr.2012.09.004, hdl.handle.net/1765/65271
Respiratory Medicine Case Reports
Department of Pediatrics

Razenberg, F.G.E.M, Heynens, J.W.C.M, de Vries, G.J, Duijts, L, de Jongste, J.C, de Blic, J, & Rosias, P.P.R. (2012). Clinical presentation of Churg-Strauss syndrome in children. Respiratory Medicine Case Reports, 7(1), 4–7. doi:10.1016/j.rmcr.2012.09.004