The aim of this study was to assess the efficacy of non-pharmacological prophylactic treatments of migraine in children. Databases were searched from inception to June 2004 and references were checked. We selected controlled trials reporting the effects of non-pharmacological prophylactic treatments in children with migraine. We assessed trial quality using the Delphi list and extracted data. Analyses were carried out according to type of intervention. A total of 19 trials were included. Relaxation, relaxation + biofeedback, relaxation + biofeedback + cognitive behavioural treatment were more effective compared with waiting list controls. Relaxation + behavioural therapy was more effective than placebo. There is conflicting evidence for the use of oligoantigenic diets. A few non-pharmacological treatments such as relaxation may be effective as prophylactic treatment for migraine in children. Because of the small number of studies and the methodological shortcomings, conclusions on effectiveness have to be drawn with caution.

Additional Metadata
Keywords Behavioural treatment, Children, Migraine, Randomized clinical trial, Systematic review
Persistent URL dx.doi.org/10.1111/j.1468-2982.2005.01046.x, hdl.handle.net/1765/65430
Journal Cephalalgia: an international journal of headache
Citation
Damen, L, Bruijn, J.K.J, Koes, B.W, Berger, M.Y, Passchier, J, & Verhagen, A.P. (2006). Prophylactic treatment of migraine in children. Part 1. A systematic review of non-pharmacological trials. Cephalalgia: an international journal of headache (Vol. 26, pp. 373–383). doi:10.1111/j.1468-2982.2005.01046.x