Background. Cervical lymphoepithelioma-like carcinoma (LELC) is a rare variant of squamous cell carcinoma of the cervix. Association with Epstein-Barr virus (EBV) is still controversial. EBV has been demonstrated in Asian women with cervical LELC. In Western women, human papillomavirus (HPV) might play a role in the etiology. Case. We describe a 44-year-old Caucasian woman with a lymphoepithelioma-like carcinoma of the cervix without EBV, but in the presence of multiple HPV infection. Conclusion. Our case supports a possible different pathway of development of cervical LELC in Western women as compared to Asian women.

Cervical carcinoma, Epstein-Barr, Human papillomavirus, Lymphoepithelioma-like carcinoma
dx.doi.org/10.1016/j.ygyno.2005.01.016, hdl.handle.net/1765/67512
Gynecologic Oncology
Department of Pathology

Bais, A.G, Kooi, G.S, Teune, T.M, Ewing, P.C, & Ansink, A.C. (2005). Lymphoepithelioma-like carcinoma of the uterine cervix: Absence of Epstein-Barr virus, but presence of a multiple human papillomavirus infection. Gynecologic Oncology, 97(2), 716–718. doi:10.1016/j.ygyno.2005.01.016