Is paromomycin the drug of choice for eradication of Dientamoeba fragilis in adults?
International Journal for Parasitology: Drugs and Drug Resistance , Volume 2 p. 162- 165
Dientamoeba fragilis is a debated protozoan parasite that is often detected in stools of patients with chronic gastro-intestinal complaints. A retrospective follow-up study of a large cohort of patients was performed to better understand the natural course of the infection and possible treatment options. D. fragilis was spontaneously cleared in 41% of untreated cases. With an eradication rate of 98%, treatment with paromomycin appeared more effective than treatment with clioquinol (83%) or metronidazole (57%).
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|International Journal for Parasitology: Drugs and Drug Resistance|
|Organisation||Department of Medical Microbiology and Infectious Diseases|
van Hellemond, J.J, Molhoek, N, Koelewijn, R, Wismans, P.J, & van Genderen, P.J.J. (2012). Is paromomycin the drug of choice for eradication of Dientamoeba fragilis in adults?. International Journal for Parasitology: Drugs and Drug Resistance, 2, 162–165. doi:10.1016/j.ijpddr.2012.03.002