The use of the Immulite Automated Immunoassay system is becoming an increasingly popular method for accurate and fast measurement of sIL-2R in serum. Here, we report that detection of sIL-2R using the Immulite Immunoassay system in serum samples of patients who are treated with basiliximab, a monoclonal antibody against the alpha-chain of the IL-2 receptor, may lead to false measurements.

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Journal of Immunological Methods
Department of Surgery

Warlé, M., Kwekkeboom, J., Tilanus, H., & Metselaar, H. (2003). Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system. Journal of Immunological Methods, 275(1-2), 133–136. doi:10.1016/S0022-1759(03)00016-4