Information processing in patients with early and continuously-treated phenylketonuria
European Journal of Pediatrics , Volume 154 - Issue 9 p. 739- 746
A total of 33 patients with early and continuously-treated phenylketonuria (PKU) between 7 and 16 years of age and 33 matched controls participated in a study examining perceptual, central, and response-related mechanisms of information processing. The specific mechanisms studied were: perceptual filtering, memory search, response selection, response execution, and motor presetting. In addition, groups were compared on mean intelligence level and task oriented behaviour. The performance of the PKU patients practically matched that of the controls on all three tasks, suggesting that PKU patients who are continuously maintained on a well-controlled phenylalanine-restricted diet are not impaired in the elementary mechanisms of information processing. Furthermore, groups did not differ in mean IQ or task-oriented behaviour.
|European Journal of Pediatrics|
Stemerdink, B.A, van der Meere, J.J, van der Molen, M.W, Kalverboer, A.F, Hendrikx, M.M.T, Huisman, J, … Verkerk, P.H. (1995). Information processing in patients with early and continuously-treated phenylketonuria. European Journal of Pediatrics, 154(9), 739–746. doi:10.1007/BF02276719