Introduction: In attempting to improve local tumor control by higher doses of radiation, there has been a resurgence of interest in the implementation of brachytherapy in the management of primary and recurrent cancers of the nasopharynx. Brachytherapy with its steep dose fall-off is of particular interest because of the proximity of critical dose limiting structures. Recent developments in brachytherapy, such as the introduction of pulsed-dose-rate and high-dose-rate computerized afterloaders, have encouraged further evolution of brachytherapy techniques. Materials and methods: We have designed an inexpensive, re-usable and flexible silicone applicator, tailored to the shape of the soft tissues of the nasopharynx, which can be used with either low-dose-rate brachytherapy or high (pulsed)- dose-rate remote controlled afterloaders. Results and conclusions: This Rotterdam nasopharynx applicator proved to be easy to introduce, patient friendly and can remain in situ for the duration of the treatment (2-6 days). The design, technique of application and the first consecutive 5 years of clinical experience in using this applicator are presented.

Applicator, Brachytherapy, Endocavitary, High- dose-rate, Low-dose-rate, Nasopharynx
dx.doi.org/10.1016/S0167-8140(97)00105-9, hdl.handle.net/1765/69442
Radiotherapy & Oncology
Erasmus MC: University Medical Center Rotterdam

Levendag, P.C, Peters, R, Meeuwis, C.A, Visch, I, Sipkema, D, de Pan, C, & Schmitz, P.I.M. (1997). A new applicator design for endocavitary brachytherapy of cancer in the nasopharynx. Radiotherapy & Oncology, 45(1), 95–98. doi:10.1016/S0167-8140(97)00105-9