Animal models of cystic fibrosis, in particular several different mutant mouse strains obtained by homologous recombination, have contributed considerably to our understanding of CF pathology. In this review, we describe and compare the main phenotypic features of these models. Recent and possible future developments in this field are discussed.

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doi.org/10.1016/j.jcf.2004.05.039, hdl.handle.net/1765/70079
Journal of Cystic Fibrosis
Biophysical Genomics, Department Cell Biology & Genetics

Scholte, B., Davidson, D., Wilke, M., & de Jonge, H. (2004). Animal models of cystic fibrosis. Journal of Cystic Fibrosis (Vol. 3, pp. 183–190). doi:10.1016/j.jcf.2004.05.039