2005-02-02
Polycystic Ovary Syndrome: Pathophysiology, Phenotype Expression and Clinical Implications
Publication
Publication
Polycysteus ovarium syndroom: pathofysiologie, fenotype expressie en klinische implicaties
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive age women and a major cause of subfertility. Women with PCOS might present with a number of various features and hence PCOS does not seem to be a clear-cut clinical phenomenon. In order to elucidate the background and pathophysiology of all symptoms displayed in PCOS it might be helpful to focus on these specific characteristics and features. In this chapter pathophysiology of ovarian dysfunction is highlighted. Additionally, several characteristic PCOS features used for classification and involved in phenotypical heterogeneity, will be briefly described. Furthermore, the complexity of research regarding the genetic component involved in the disease is discussed. Finally, the clinical implications of differences in phenotype expression are mentioned. In addition, the objectives of the present thesis are described in brief.
| Additional Metadata | |
|---|---|
| , | |
| Amphia Ziekenhuis, Fauser, Prof. Dr. B.J.C.M. (promotor), Haga Holland Trading BV, Hitachi Medical Systems BV, Medical Dynamics, Medical Systems Europe BV, Memidis Pharma, Organon Nederland BV, Pfizer & Toshiba, Schering Nederland BV, Serono Benelux bv & Ferring Geneesmiddelen BV | |
| Erasmus University Rotterdam | |
| hdl.handle.net/1765/7011 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
|
Mulders, A. (2005, February 2). Polycystic Ovary Syndrome: Pathophysiology, Phenotype Expression and Clinical Implications. Retrieved from http://hdl.handle.net/1765/7011 |
|
