2013-07-16
Identification and Characterization of Two Novel Viruses in Ocular Infections in Reindeer
Publication
Publication
PLoS ONE , Volume 8 - Issue 7
A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifer tarandus tarandus) in Norway during an outbreak of infectious eye disease, possibly a very early stage of infectious keratoconjunctivitis (IKC). Large scale molecular virus screening, based on host nucleic acid depletion, sequence-independent amplification and next-generation sequencing of partially purified viral nucleic acid, revealed the presence of a new papillomavirus in 2 out of 8 eye swab samples and a new betaherpesvirus in 3 out of 8 eye swab samples collected from animals with clinical signs and not in similar samples in 9 animals without clinical signs. Whether either virus was responsible for causing the clinical signs or in any respect was associated to the disease condition remains to be determined.
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| doi.org/10.1371/journal.pone.0069711, hdl.handle.net/1765/70524 | |
| PLoS ONE | |
| Organisation | Department of Virology |
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Smits, S., Schapendonk, C., van Leeuwen, M., Kuiken, T., Bodewes, R., Stalin Raj, V. S., … Osterhaus, A. (2013). Identification and Characterization of Two Novel Viruses in Ocular Infections in Reindeer. PLoS ONE, 8(7). doi:10.1371/journal.pone.0069711 |
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