2012-07-01
Frequency domain multiplexing for speckle reduction in optical coherence tomography
Publication
Publication
Journal of Biomedical Optics , Volume 17 - Issue 7
Quantitative analysis of optical coherence tomography data can be strongly hampered by speckle. Here, we introduce a new method to reduce speckle, which leverages from Fourier-domain configurations and operates on individual axial scans. By subdividing the digitized spectrum into a number of distinct narrower windows, each with a different center frequency, several independent speckle patterns result. These can be averaged to yield a lower-resolution image with strongly reduced speckle. The full resolution image remains available for human interpretation; the low resolution version can be used for parametric imaging or quantitative analysis. We demonstrate this technique using intravascular optical frequency domain imaging data acquired in vivo.
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doi.org/10.1117/1.JBO.17.7.076018, hdl.handle.net/1765/70773 | |
Journal of Biomedical Optics | |
Organisation | Department of Cardio-Thoracic Surgery |
van Soest, G., Villiger, P. M., Regar, E., Tearney, G., Bouma, B., & van der Steen, T. (2012). Frequency domain multiplexing for speckle reduction in optical coherence tomography. Journal of Biomedical Optics, 17(7). doi:10.1117/1.JBO.17.7.076018 |