Host specific T-cell response is critical for the outcome of Helicobacter pylori infection. In genetically susceptible individuals, H. pylori can activate gastric CD4+ Th1 cells that recognize cross-reactive epitopes shared by H. pylori proteins and self H+, K+-ATPase, leading to gastric autoimmunity via molecular mimicry.

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doi.org/10.1016/j.micinf.2004.10.001, hdl.handle.net/1765/71115
Microbes and Infection: a journal on infectious agents and host defenses
Department of Medical Microbiology and Infectious Diseases

D'Elios, M. M., Bergman, M., Amedei, A., Appelmelk, B., & Del Prete, G. (2004). Helicobacter pylori and gastric autoimmunity. Microbes and Infection: a journal on infectious agents and host defenses, 6(15), 1395–1401. doi:10.1016/j.micinf.2004.10.001