1995
Dialysis of isolated low density lipoprotein induces a loss of lipophilic antioxidants and increases the susceptibility to oxidation in vitro
Publication
Publication
Atherosclerosis , Volume 117 - Issue 1 p. 139- 144
We determined the effects of different dialysis conditions on the antioxidant content, duration of the lag phase and oxidation rate of LDL. Dialysis for 22 h resulted in a 56%–66% reduction in the concentrations of β-carotene, lycopene and α-tocopherol. The lag phase of copper-induced oxidation of freshly isolated LDL was considerably longer than that of LDL dialysed for 22 or 44 h. Our data show that dialysis may result in LDL preparations with antioxidant compositions that are not truly representative of freshly isolated lipoproteins.
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| , , , , | |
| doi.org/10.1016/0021-9150(95)05555-B, hdl.handle.net/1765/71492 | |
| Atherosclerosis | |
| Organisation | Department of Biochemistry |
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Scheek, L., Wiseman, S., Tijburg, L., & van Tol, A. (1995). Dialysis of isolated low density lipoprotein induces a loss of lipophilic antioxidants and increases the susceptibility to oxidation in vitro. Atherosclerosis, 117(1), 139–144. doi:10.1016/0021-9150(95)05555-B |
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