A 44-year-old man suffering from cytogenetically and molecularly proven Philadelphia translocation-positive chronic myelogenous leukemia in chronic phase was treated with busulfan for 18 months and studied during a follow-up period of 13 years. Hematologically and cytogenetically, he attained a continuing complete remission, although at one point (9.5 years) at least, after attaining complete remission molecular analysis indicated the presence of minimal residual disease.

Additional Metadata
Keywords Busulfan, Chronic myelogenous leukemia, Cytogenetic, Minimal residual disease, Polymerase chain reaction
Persistent URL dx.doi.org/10.1007/s002770050188, hdl.handle.net/1765/71493
Journal Annals of Hematology
Citation
Mandigers, C, Mensink, E.J.B.M, Geurts van Kessel, A.H.M, van der Plas, D, Haanen, C, Hagemeÿer, A, & de Witte, T. (1996). A long-lasting, complete hematologic and cytogenetic remission of chronic myelogenous leukemia after treatment with busulfan alone. Annals of Hematology, 72(6), 371–373. doi:10.1007/s002770050188