Bacterial cholangitis causing secondary sclerosing cholangitis: A case report
B M C Gastroenterology , Volume 2
Background: Although bacterial cholangitis is frequently mentioned as a cause of secondary sclerosing cholangitis, it appears to be extremely rare, with only one documented case ever reported. Case presentation: A 48-year-old woman presented with an episode of acute biliary pancreatitis that was complicated by pancreatic abcess formation. After 3 months she had an episode of severe pyogenic (E. Coli) cholangitis that recurred over the subsequent 7 months on a further two occasions. Initially, cholangiography suggested the presence of extra-biliary intrahepatic abcesses while repeated investigations demonstrated development of multiple segmental biliary duct strictures. After maintenance antibiotic treatment was started, no episodes of cholangitis occurred over a 14-month period. Conclusions: Sclerosing cholangitis can rapidly develop after an episode of bacterial cholangitis. Extra-biliary involvement of the hepatic parenchyma with abcess formation may be a risk factor for developing this rare but particularly severe complication.
|B M C Gastroenterology|
|Organisation||Department of Gastroenterology & Hepatology|
ter Borg, P.C.J, van Buuren, H.R, & Depla, A.C.T.M. (2002). Bacterial cholangitis causing secondary sclerosing cholangitis: A case report. B M C Gastroenterology, 2. doi:10.1186/1471-230X-2-14