2012-05-01
Proteomic analysis of the microenvironment of developing oocytes
Publication
Publication
Proteomics , Volume 12 - Issue 9 p. 1463- 1471
We utilized a setup based on extensive pre-fractionation of proteolytic peptides and nanoflow reversed-phase LC-MS/MS to identify the (sub)proteome of human follicular fluid (FF). In this in-depth screen, 246 specific proteins were identified, the majority of which are involved in coagulation- and immune-response pathways. Our aim is to define a set of FF protein markers, which could predict oocyte quality.
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doi.org/10.1002/pmic.201100240, hdl.handle.net/1765/72247 | |
Proteomics | |
Organisation | Department of Gynaecology & Obstetrics |
Twigt, J., Steegers-Theunissen, R., Bezstarosti, K., & Demmers, J. (2012). Proteomic analysis of the microenvironment of developing oocytes. Proteomics, 12(9), 1463–1471. doi:10.1002/pmic.201100240 |