Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in Peutz-Jeghers syndrome

Alhopuro, Pia; Katajisto, P.; Lehtonen, R.; Ylisaukko-oja, Sanna; Näätsaari, L.; Karhu, Auli; Westerman, Anne Marie; Wilson, Paul; de Rooij, Felix; Vogel, T.; Moeslein, Gabriela; Tomlinson, Ian; Aaltonen, Lauri; Mäkelä, M.J.; Launonen, V.

doi:10.1038/sj.bjc.6602454

Mutations in LKB1 lead to Peutz-Jeghers syndrome (PJS). However, only a subset of PJS patients harbours LKB1 mutations. We performed a mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in 28 LKB1-negative PJS patients. No disease-causing mutations were detected in the studied genes in PJS patients from different European populations.

Additional Metadata
Keywords	BRG1, LKB1, MO25α, Peutz-Jeghers syndrome, STRADα
Persistent URL	doi.org/10.1038/sj.bjc.6602454, hdl.handle.net/1765/72948
Journal	British Journal of Cancer
Organisation	Department of Internal Medicine
Citation APA Style AAA Style APA Style Cell Style Chicago Style Harvard Style IEEE Style MLA Style Nature Style Vancouver Style American-Institute-of-Physics Style Council-of-Science-Editors Style BibTex Format Endnote Format RIS Format CSL Format DOIs only Format	Alhopuro, P., Katajisto, P., Lehtonen, R., Ylisaukko-oja, S., Näätsaari, L., Karhu, A., … Launonen, V. (2005). Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in Peutz-Jeghers syndrome. British Journal of Cancer, 92(6), 1126–1129. doi:10.1038/sj.bjc.6602454

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in Peutz-Jeghers syndrome

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Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADα, and MO25α, in Peutz-Jeghers syndrome

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