1998-06-01
Improved quantification of myocardial mass by three-dimensional echocardiography using a deposit contrast agent
Publication
Publication
Ultrasound in Medicine & Biology , Volume 24 - Issue 5 p. 647- 653
The aim of the study was to assess the usefulness of a novel contrast agent in combination with three-dimensional echocardiography for improved mass quantification. Three-dimensional reconstruction of left ventricular myocardium was performed from images obtained with rotational epicardial acquisition in eight open-chested pigs, before and after injection of a deposit contrast agent, Quantison Depot(TM). Three-dimensional echocardiographic myocardial mass values were in excellent agreement with weighed mass (differences -1.6 ± 5.0 g for end-diastolic frame, -2.8 ± 4.5 g for end-systolic, 1.0 ± 1.0 g for end-diastolic with contrast and 0.6 ± 2.0 g for end-systolic with contrast, p = NS). Left ventricular mass measurements after contrast injection were more accurate and had less measurement variability. In conclusion, myocardial contrast enhancement improves left ventricular mass calculation with three-dimensional echocardiography.The aim of the study was to assess the usefulness of a novel contrast agent in combination with three-dimensional echocardiography for improved mass quantification. Three-dimensional reconstruction of left ventricular myocardium was performed from images obtained with rotational epicardial acquisition in eight open-chested pigs, before and after injection of a deposit contrast agent, Quantison DepotTM. Three-dimensional echocardiographic myocardial mass values were in excellent agreement with weighed mass (differences -1.6±5.0 g for end-diastolic frame, -2.8±4.5 g for end-systolic, 1.0±1.0 g for end-diastolic with contrast and 0.6±2.0 g for end-systolic with contrast, p = NS). Left ventricular mass measurements after contrast injection were more accurate and had less measurement variability. In conclusion, myocardial contrast enhancement improves left ventricular mass calculation with three-dimensional echocardiography.
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| doi.org/10.1016/S0301-5629(98)00035-0, hdl.handle.net/1765/74127 | |
| Ultrasound in Medicine & Biology | |
| Organisation | Department of Cardiology |
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Kasprzak, J., Vletter, W., van Meegen, J., Nosir, Y., Johnson, R., ten Cate, F., & Roelandt, J. (1998). Improved quantification of myocardial mass by three-dimensional echocardiography using a deposit contrast agent. Ultrasound in Medicine & Biology, 24(5), 647–653. doi:10.1016/S0301-5629(98)00035-0 |
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