Purpose: The chance of recurrence of poor fertilization in a second in vitro fertilization (IVF) cycle was assessed. Methods: Total fertilization failure was defined, and the relationship between the fertilization rate and the number of motile sperm cells per milliliter of semen was assessed. Patients with a total fertilization failure or poor fertilization (20% or less of the oocytes fertilized) were divided into three subgroups with different chances of fertilization and were followed in a subsequent IVF cycle. Results: The recurrence rate of total fertilization failure was high in all three groups (45-70%), and poor fertilization frequently occurred in the second cycle (50-75%). Conclusions: Poor fertilization frequently recurs in the second IVF cycle. The use of intracytoplasmic sperm injection could be considered after fertilization of 20% or less of oocytes in the first cycle, irrespective of the number of motile sperm cells per milliliter of semen.

Additional Metadata
Keywords Fertilization failure, Poor fertilization
Persistent URL dx.doi.org/10.1023/A:1022570120207, hdl.handle.net/1765/74336
Journal Journal of Assisted Reproduction and Genetics
Citation
Roest, J, van Heusden, A.M, Zeilmaker, G.H, & Verhoeff, A. (1998). Treatment policy after poor fertilization in the first IVF cycle. Journal of Assisted Reproduction and Genetics, 15(1), 18–21. doi:10.1023/A:1022570120207