Interleukin-10 (IL-10) is a potent immunomodulatory cytokine, whose cellular targets have not yet been precisely identified. Mice bearing a dendritic cell (DC)-specific defect in the IL-10 receptor mice exhibit exaggerated T-cell reactivation in the skin, highlighting a key function of DCs in the maintenance of local immune homeostasis.

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doi.org/10.4161/onci.23186, hdl.handle.net/1765/74682
OncoImmunology
Department of Immunology

Clausen, B., & Girard-Madoux, M. (2013). IL-10 control of dendritic cells in the skin. OncoImmunology, 2(3). doi:10.4161/onci.23186