Drug Safety in Children: Focus on hepatic concerns

Ferrajolo, Carmen

Abstract

As defined by World Health Organization (WHO), pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem (adverse drug reactions, ADRs). The aims of pharmacovigilance are to improve patient care and patient safety in relation to the use of medicines and to support public health programmes by providing reliable, balanced information on the risk-benefit profile of medicines.

Additional Metadata
Keywords	drug safety, children, hepatic injury, liver injury
Promotor	M.C.J.M. Sturkenboom (Miriam) , F. Rossi (Francesco)
Publisher	Erasmus University Rotterdam
ISBN	978-94-6169-579-6
Persistent URL	hdl.handle.net/1765/77131
Note	Part of this research was conducted within EC-funded projects: • GRiP has received funding from the European Commission Seventh Framework Pro- gramme FP7/2007-2013 under grant agreement n° 261060. (Chapters 2.1, 2.2, and 6.1) • EU-ADR has been funded by the European Commission Seventh Framework Programme FP7/2007-2013 under grant n° 215847-the EU-ADR project. (Chapters 4.1 and 5.1) Financial support for printing this thesis was generously provided by Italian Society of Pharmacology (SIF); Pedianet database, Padua, Italy; Interdisciplinary Processing of Clinical Information (IPCI) group of the Department of Medical Informatics, Erasmus Medical Centre University, Rotterdam; and the Erasmus Medical Centre University of Rotterdam. Data from the Rete Nazionale di Farmacovigilanza of the Italian Medicines Agency (AIFA), the Adverse Event Reporting System of the Food and Drug Administration (FDA), and the VigiBase of the WHO Collaborating Centre for International Drug Monitoring were used in Chapters 2.1, 2.2, 3.1 respectively. The contributions of the general practitioners/family paediatricians participating in the IPCI, Health Search/CDS, and Pedianet are greatly acknowledged.
Grant	This work was funded by the European Commission 7th Framework Programme; grant id fp7/215847 - Exploring and understanding adverse drug reactions by integrative mining of clinical records and biomedical knowledge (EU-ADR), This work was funded by the European Commission 7th Framework Programme; grant id fp7/261060 - Global Research in Paediatrics (GRIP)
Organisation	Erasmus MC: University Medical Center Rotterdam
Citation APA Style AAA Style APA Style Cell Style Chicago Style Harvard Style IEEE Style MLA Style Nature Style Vancouver Style American-Institute-of-Physics Style Council-of-Science-Editors Style BibTex Format Endnote Format RIS Format CSL Format DOIs only Format	Ferrajolo, C. (2014, November 12). Drug Safety in Children: Focus on hepatic concerns. Retrieved from http://hdl.handle.net/1765/77131