2015-09-11
Transfusion-Related Acute Lung Injury
Publication
Publication
The role of donor antibodies
Transfusiegerelateerde acute longschade : de rol van donor-antistoffen
Abstract
Transfusion-related acute lung injury (TRALI) is a serious complication of blood transfusion, which causes serious morbidity and is the leading cause of transfusion-associated mortality according to the FDA. The majority of TRALI cases (up to 89%) are thought to be antibody-mediated TRALI, caused by the passive infusion of white blood cell (WBC)- reactive antibodies, present in plasma-containing blood products. This thesis focuses on the role of donor WBC-reactive antibodies in TRALI, and the translation to preventive strategies.
| Additional Metadata | |
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| , , , , | |
| D.J. van Rhenen (Dirk Jan) | |
| The printing of this thesis was financially supported by: Sanquin Bloedvoorziening and Erasmus Universiteit Rotterdam | |
| Erasmus University Rotterdam | |
| hdl.handle.net/1765/78595 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Mathijssen-van Stein, D. (2015, September 11). Transfusion-Related Acute Lung Injury: The role of donor antibodies. Retrieved from http://hdl.handle.net/1765/78595 |
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