The findings described in this thesis add to the evidence for peripheral alterations in schizophrenia and suggest that distinct molecular endophenotypes in schizophrenia patients may be associated with the disease pathophysiology or response to treatment.

This research contributes to de-convoluting the complexity of schizophrenia and drug response mechanisms. Potential applications of these findings in personalised medicine approaches include identification of patient subgroups more likely to respond to a particular antipsychotic drug or adjunctive treatment, and developing decision rules for continuation or termination of a selected treatment.

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S. Bahn (Sabine) , C.I. de Zeeuw (Chris) , N.J.M. van Beveren (Nico)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Tomasik, J. (2014, December 16). Blood-based Biomarkers for Personalised Medicine Applications in Schizophrenia. Retrieved from http://hdl.handle.net/1765/79093