2006-06-21
Modulography: elasticity imaging of atherosclerotic plaques
Publication
Publication
Modulography: visualisatie van de elasticiteit van atherosclerotische plaques
Modulography is an experimental elasticity imaging method. It has potential to become an all-in-one in vivo tool (a) for detecting vulnerable atherosclerotic coronary plaques, (b) for assessing information related to their rupture-proneness and (c) for imaging their elastic material composition. Modulography determines a cross-sectional image of the elasticity distribution (=Young's modulus) from deformation (=strain) that is processed from intravascular ultrasound (IVUS) measurements. By looking at this image, cardiologists and other researchers can directly identify and characterize soft and stiff plaque-components of thin-cap fibroatheromas and of heterogeneous plaques. As a diagnostic and pharmaceutical screening tool, Modulography may contribute to the reduction of heart attacks and strokes, which are the number-one killers in westernized societies.
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| Bristol-Myers Squibb & Bristol-Myers Squibb MedicalImagingCardialysis, Dutch Technology Foundation (STW), Interuniversity Cardiology Institute of the Netherlands, Merck Sharp & Dohme BV, Netherlands Heart Foundation, Novartis Pharma AG, OrbusNeich, Pfizer, Sanofi-Aventis, Volcano Corporation | |
| A.F.W. van der Steen (Ton) , P.W.J.C. Serruys (Patrick) | |
| Erasmus University Rotterdam | |
| hdl.handle.net/1765/7922 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Baldewsing, R. (2006, June 21). Modulography: elasticity imaging of atherosclerotic plaques. Retrieved from http://hdl.handle.net/1765/7922 |
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