2015
Ocular Hypertension and the Risk of Blindness
Publication
Publication
Journal of Glaucoma , Volume 24 - Issue 1 p. 9- 11
Purpose: To estimate the risk of blindness in patients with ocular
hypertension (OHT) using an appropriate model and current
empirical data.
Design: A Markov model with data from a systematic literature
review.
Methods: A Markov model with 3 health states was built: OHT,
primary open-angle glaucoma (POAG), and unilateral blindness.
Literature was searched for reports on conversion from OHT to
POAG and progression from POAG to blindness, to estimate a
range of annual conversion and progression probabilities. The
model had a cycle length of 1 year.
Results: The 15-year risk estimates ranged from 3.1% to 9.4% in
untreated, and from 0.9% to 8.6% in treated patients with OHT.
The ranges were the result of differences in patient populations,
treatments, and outcome definitions in currently available empirical
data.
Conclusions: The best estimates of the 15-year risk of unilateral
blindness in patients with OHT, based on the currently available
empirical data and an appropriate model, show that the risk is <10%.
Additional Metadata | |
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doi.org/10.1097/IJG.0b013e318287ac75, hdl.handle.net/1765/79388 | |
Journal of Glaucoma | |
Organisation | Erasmus School of Health Policy & Management (ESHPM) |
van Gestel, A., Webers, C. A. B., Beckers, H., Peeters, A., Severens, H., & Schouten, J. S. A. G. (2015). Ocular Hypertension and the Risk of Blindness. Journal of Glaucoma, 24(1), 9–11. doi:10.1097/IJG.0b013e318287ac75 |