This thesis aimed to optimize the predictive and prognostic information that can be obtained from Circulating Tumor cells (CTC) and Circulating Endothelial Cells (CEC) in whole blood by improving and standardization of their detection and characterization methods in patients with solid malignancies. Both CTC and CEC are promising biomarkers for research purpose and patient management, that can be easily obtained by a non-invasive blood sampling (i.e. liquid biopsy) on multiple time points.

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J.A. Foekens (John) , J.W. Gratama (Jan-Willem)
Erasmus University Rotterdam
This research project was in part financially supported by Cancer Genomics Netherlands/Netherlands Organization for Scientific Research (NWO), IQ products BV and Janssen, LLC, Raritan, NJ. Publication of this thesis was financially supported by kind contributions from: Department of Medical Oncology, Erasmus MC Cancer Institute Rotterdam, Erasmus University Rotterdam, Bio-Connect BV Boehringer Ingelheim BV, Chipsoft BV, Distrilab BV, GR Instruments and Libra Diagnostica.
hdl.handle.net/1765/79634
Erasmus MC: University Medical Center Rotterdam

Kraan, J. (2015, November 18). Cell-based monitoring of cancer. Retrieved from http://hdl.handle.net/1765/79634