2015
Coronavirus spike-receptor interactions
Publication
Publication
The history of coronaviruses started in the 1930s when avian infectious bronchitis virus (IBV) was first described as the causative agent of infectious bronchitis in poultry flocks (1-2). In the mid-1960s, two human coronaviruses, 229E (HCoV- 229E) and OC-43 (HCoV-OC43), were identified as pathogens for common-colds in humans (3-5). Early studies on human coronaviruses were primarily focused on the epidemiology of these viruses using serological techniques. Coronaviruses were demonstrated to contribute to as much as 35% of respiratory infections in humans during epidemics (6). In 1975, the Coronaviridae family with one genus, coronavirus, was officially established, referring to the crown-like appearance of spikes on the surface of these viruses (7).
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hdl.handle.net/1765/79789 | |
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Organisation | Erasmus MC: University Medical Center Rotterdam |
Mou, H. (2015). Coronavirus spike-receptor interactions. Retrieved from http://hdl.handle.net/1765/79789 |