Sleep problems in children with autism spectrum disorders (ASD) are under-recognized and under-treated. Identifying treatment value accounting for health effects on family members (spillovers) could improve the perceived cost-effectiveness of interventions to improve child sleep habits. A prospective cohort study (N = 224) was conducted with registry and postal survey data completed by the primary caregiver.Wecalculated quality of life outcomes for the child and the primary caregiver associated with treatments to improve sleep in the child based on prior clinical trials. Predicted treatment effects for melatonin and behavioral interventions were similar in magnitude for the child and for the caregiver. Accounting for caregiver spillover effects associated with treatments for the child with ASD increases treatment benefits and improves cost-effectiveness profiles.

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The project was supported by a Grant (R01MH089466) with JMT and KAK serving as principal investigators and a Grant (R03MH102495) with NP as the principal investigator both from the National Institute of Mental Health.
doi.org/10.1007/s10803-015-2507-5, hdl.handle.net/1765/80246
Journal of Autism and Developmental Disorders
Erasmus School of Health Policy & Management (ESHPM)

Tilford, J. M., Payakachat, N., Kuhlthau, K., Pyne, J., Kovacs, E., Brouwer, W., & Frye, R. (2015). Sleep problems for children with autism and caregiver spillover effects. Journal of Autism and Developmental Disorders, 45(11), 3613–3623. doi:10.1007/s10803-015-2507-5