To identify unknown human viruses, we analyzed serum and cerebrospinal fluid samples from patients with unexplained paraplegia from Malawi by using viral metagenomics. A novel cyclovirus species was identified and subsequently found in 15% and 10% of serum and cerebrospinal fluid samples, respectively. These data expand our knowledge of cyclovirus diversity and tropism.

doi.org/10.3201/eid1909.130404, hdl.handle.net/1765/81107
Emerging Infectious Diseases - (Open Access)
Erasmus MC: University Medical Center Rotterdam

Smits, S., Zijlstra, E., van Hellemond, J., Schapendonk, C., Bodewes, R., Schürch, A., … Osterhaus, A. (2013). Novel cyclovirus in human cerebrospinal fluid, Malawi, 2010-2011. Emerging Infectious Diseases - (Open Access), 19(9), 1511–1513. doi:10.3201/eid1909.130404