2011-02-01
New drug-eluting stents with biodegradable polymers
Publication
Publication
Minerva Cardioangiologica: a journal on heart and vascular diseases , Volume 59 - Issue 1 p. 31- 37
Current drug-eluting stents (DES) perform well compared to bare metal stents. However, long-term rates of major adverse events and in particular repeat revascularization by PCI are still an issue. In this concise review we will discuss the possibilities of biodegradable coatings to improve biocompatibility of DES. Among the various members of the synthetic biodegradable polymer family, polyesters are widely used and attractive for their ease of degradation, with degradation products often being resorbed through general metabolic pathways. A new development is surface functionalization of polyesters to improve endothelialization.
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| hdl.handle.net/1765/81177 | |
| Minerva Cardioangiologica: a journal on heart and vascular diseases | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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van der Giessen, W., & van Beusekom, H. (2011). New drug-eluting stents with biodegradable polymers. Minerva Cardioangiologica: a journal on heart and vascular diseases, 59(1), 31–37. Retrieved from http://hdl.handle.net/1765/81177 |
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