Objective: The aim of this study was to analyze the correlation between the extent of diameter change from standing to supine position ("postural diameter change," PDC), and patient or duplex ultrasound (DUS) characteristics in lower limbs with and without saphenous trunk (ST) reflux. Methods: Measurements were carried out in 193 limbs with primary great saphenous vein, anterior accessory saphenous vein, or small saphenous vein reflux, and 48 control limbs without ST reflux. The inner diameter of the ST was measured with DUS in the standing and lying positions. The PDC, calculated as a percentage, followed the formula: (standing diameter - lying diameter)/standing diameter × 100. Clinical findings (according to the highest "C" - of the CEAP classification), venous clinical severity score, body mass index (BMI), time of visit, and inside and outside temperature were documented. Limbs were divided into two groups using the median value of positional variability as a cut off to increase interpretability of the analysis. Results: The median PDC of the ST was 19% in limbs with ST reflux compared with 24% in control limbs (p = .16). In limbs with and without ST reflux, only older age and increased BMI were independently associated with a low PDC of the ST (R2 0.13). In limbs with ST reflux, median PDC was significantly lower in C4-C6 (16%, interquartile [IQR] 8-21) than in C0-C1 (23%, IQR 12-35) or C2-C3 limbs (21%, IQR 11-33; p = .016). In addition, PDC was significantly lower in veins with a large diameter (>7 mm) than in those with a small diameter (p = .003). Conclusion: Low PDC of the ST correlates with older age and increased BMI. Whether PDC might become a useful additional DUS tool to classify the severity of chronic venous disease and thereby influence the management strategy should be further investigated.

Additional Metadata
Keywords Chronic venous disease, Postural diameter change, Saphenous diameter, Saphenous trunk
Persistent URL dx.doi.org/10.1016/j.ejvs.2016.02.019, hdl.handle.net/1765/81273
Journal European Journal of Vascular and Endovascular Surgery
van der Velden, S.K, de Maeseneer, M.G.R, Pichot, O, Nijsten, T.E.C, & van den Bos, R.R. (2016). Postural Diameter Change of the Saphenous Trunk in Chronic Venous Disease. European Journal of Vascular and Endovascular Surgery, 51(6), 831–837. doi:10.1016/j.ejvs.2016.02.019