2015-11-12
The HysNiche trial: Hysteroscopic resection of uterine caesarean scar defect (niche) in patients with abnormal bleeding, a randomised controlled trial
Publication
Publication
BMC Women's Health , Volume 15 - Issue 1
Background: A caesarean section (CS) can cause a defect or disruption of the myometrium at the site of the uterine scar, called a niche. In recent years, an association between a niche and postmenstrual spotting after a CS has been demonstrated. Hysteroscopic resection of these niches is thought to reduce spotting and menstrual pain. However, there are no randomised trials assessing the effectiveness of a hysteroscopic niche resection. Methods/Design: We planned a multicentre randomised trial comparing hysteroscopic niche resection to no intervention. We study women with postmenstrual spotting after a CS and a niche with a residual myometrium of at least 3 mm during sonohysterography. After informed consent is obtained, eligible women will be randomly allocated to hysteroscopic resection of the niche or expectant management for 6 months. Discussion: This trial will provide insight in the (cost)effectiveness of hysteroscopic resection of a niche versus expectant management in women who have postmenstrual spotting and a niche with sufficient residual myometrium to perform a hysteroscopic niche resection. Trial registration: Dutch Trial Register NTR3269. Registered 1 February 2012. ZonMw Grant number 80-82305-97-12030
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| doi.org/10.1186/s12905-015-0260-8, hdl.handle.net/1765/81630 | |
| BMC Women's Health | |
| Organisation | Franciscus Gasthuis & Vlietland |
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Vervoort, A. J. M. W., Van der Voet, L. F., Witmer, M., Thurkow, A. L., Radder, C. M., van Kesteren, P. J. M., … Huirne, J. (2015). The HysNiche trial: Hysteroscopic resection of uterine caesarean scar defect (niche) in patients with abnormal bleeding, a randomised controlled trial. BMC Women's Health, 15(1). doi:10.1186/s12905-015-0260-8 |
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