Treatment of Psoriasis

The chapter talks about the treatment of psoriasis, which is associated with two relatively uncommon conditions that may cause long-lasting disability as a result of severe inflammation and pustulation affecting the hands and feet. The first is now more commonly referred to as palmoplantar pustulosis, but is still widely known as chronic palmoplantar pustular psoriasis. Acropustulosis (acrodermatitis continua of Hallopeau), on the other hand, may be associated with generalized pustular psoriasis. The chapter discusses the prevalence, etiology and prognosis of the psoriasis. It describes the topical treatment of chronic plaque-type psoriasis, and focuses on effectiveness of different types of phototherapies for chronic plaque-type psoriasis. Acitretin, methotrexate, cyclosporine, adalimumab, etanercept, ustekinumab and infliximab are used for systemic treatments for limited stable chronic plaque psoriasis. The chapter also describes effective treatments for guttate psoriasis and systemic treatments for acropustulosis.

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