DNA-based techniques are frequently used to confirm the relatedness of putative outbreak isolates. These techniques often lack the discriminatory power when analyzing closely related microbes such as E. coli. Here the value of Raman spectroscopy as a typing tool for E. coli in a clinical setting was retrospectively evaluated.

doi.org/10.1007/s10096-015-2511-x, hdl.handle.net/1765/82049
European Journal of Clinical Microbiology & Infectious Diseases: an international journal on pathogenesis, diagnosis, epidemiology, therapy, and prevention of infectious diseases
Department of Dermatology

Kusters, J.G, van Leeuwen, W.B, Maquelin, K, Blok, H, Willemse, H.F, de Graaf-Miltenburg, L.A.M, … Troelstra, A. (2016). Raman spectroscopy-based identification of nosocomial outbreaks of the clonal bacterium Escherichia coli. European Journal of Clinical Microbiology & Infectious Diseases: an international journal on pathogenesis, diagnosis, epidemiology, therapy, and prevention of infectious diseases, 35(1), 83–87. doi:10.1007/s10096-015-2511-x