In vivo assessment of mitochondrial oxygen consumption
The protoporphyrin IX-triplet state lifetime technique (PpIX-TSLT) has been proposed by us as a potential clinical noninvasive tool for monitoring mitochondrial function. We have been working on the development of mitochondrial respirometry for monitoring mitochondrial oxygen tension (mitoPO2) and mitochondrial oxygen consumption (mitoVO2) in skin. In this work we describe the principles of the method in experimental animals.
|Mitochondrial oxygen consumption (mitoVO2), Mitochondrial oxygen tension (mitoPO2), Oxygen-dependent quenching, Phosphorescence quenching, Tissue oxygenation|
|Organisation||Department of Anesthesiology|
Harms, F.A, & Mik, E.G. (2015). In vivo assessment of mitochondrial oxygen consumption. doi:10.1007/978-1-4939-2257-4_20