Objective: To evaluate differences in functional parameters and reproducibility between short axis and axial slice orientation in the quantitative evaluation of the systemic right ventricle by cardiovascular magnetic resonance. Design: Cross-sectional evaluation comparing two methods (Bland-Altman). Setting: Tertiary care outpatients. Interventions: Quantitative cardiovascular magnetic resonance evaluation using short axis or axial slice orientation. Main Outcome Measures: Intraobserver variance, interobserver variance and systematic differences in systemic right ventricular volumes, ejection fraction, and mass between both methods. Patients: Twenty-two patients (mean age 33 ± 7 years) with systemic right ventricle (three with congenitally corrected transposition of the great arteries and 19 with atrially switched transposition of the great arteries). Results: Compared with short axis slices, analysis of axial slices resulted in higher end systolic volume (6.6%, P < .01), while mass (-10.8%, P < .01) and ejection fraction (-8.9%, P < .01) turned out lower. Intraobserver and interobserver reproducibility were similar for both methods when measuring end-diastolic and end-systolic volumes. However, ejection fraction and stroke volume were measured more consistently in axial orientation, while ventricular mass was measured more consistently in short axis orientation. Conclusion: There are significant differences in volume, mass, and function between measurements in axial and short axis orientation. Ejection fraction and stroke volume, which have a high clinical relevance, were measured more consistently in axial slice orientation. Consequently, we recommend using axial slice orientation in patients with a systemic right ventricle.

Cardiovascular magnetic resonance imaging, Functional evaluation, Methodology, Systemic right ventricle, Transposition of the great arteries
dx.doi.org/10.1111/chd.12182, hdl.handle.net/1765/82286
Congenital Heart Disease
Department of Radiology

van der Bom, T, Romeih, S, Groenink, M, Pieper, P.G, van Dijk, A.P.J, Helbing, W.A, … Bouma, B.J. (2015). Evaluating the systemic right ventricle by cardiovascular magnetic resonance: Short axis or axial slices?. Congenital Heart Disease, 10(1), 69–77. doi:10.1111/chd.12182