Palable purpura are the most frequently seen skin lesions in cutaneous small vessel vasculitis. The combination of nodi, livedo, necrosis and ulceration is suggestive for the diagnosis cutaneous PAN. In 30-63% of patients with cutaneous small vessel vasculitis no systemic vasculitis or other causative factors are found. It is advised to perform a thorough anamnesis and clinical investigation in all the patients with cutaneous small vessel vasculitis. In case of suspicion of vasculitis skin biopsies are needed for light microscopy as well as for immunofluorescence from a lesion of 24-48 hours old.

Biopsy, Diagnostics, Guideline, Symptoms, Vasculitis
hdl.handle.net/1765/82830
Nederlands Tijdschrift voor Dermatologie en Venereologie
Erasmus MC: University Medical Center Rotterdam

De Jong, E.M.G.J, Thio, H.B, Stegeman, C.A, & van Everdingen, J.J.E. (2010). Summary directive on vasculitis: The skin. Nederlands Tijdschrift voor Dermatologie en Venereologie, 20(2), 87–89. Retrieved from http://hdl.handle.net/1765/82830