2015
Patient Perception of Imiquimod Treatment for Actinic Keratosis and Superficial Basal Cell Carcinoma in 202 Patients
Publication
Publication
Dermatology: international journal for clinical and investigative dermatology , Volume 231 - Issue 1 p. 56- 62
Objective: To document the impact on patient-reported outcomes and health-related quality of life (HRQoL) of treatment with imiquimod cream in patients with actinic keratosis (AK) and superficial basal cell carcinoma (sBCC). Methods: This open-label, multicenter study included AK and sBCC patients eligible for treatment with imiquimod 5% cream. HRQoL was measured by the Skindex-17 and the Skin Cancer Index (SCI) and treatment satisfaction by the Treatment Satisfaction Questionnaire for Medication. Results: 118 AK patients and 84 patients with sBCC were included. Low baseline HRQoL impairment was found on both questionnaires, which remained low after treatment, except for a small dip at the end of the application period. Conclusion: Imiquimod 5% cream treatment has no clinically relevant HRQoL impact in AK and sBCC patients according to the Skindex-17 and SCI. The effect of imiquimod treatment on HRQoL may be limited or these questionnaires do not fully capture relevant issues, such as fear of recurrence.
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doi.org/10.1159/000381420, hdl.handle.net/1765/83012 | |
Dermatology: international journal for clinical and investigative dermatology | |
Organisation | Department of Dermatology |
Waalboer-Spuij, R., Holterhues, C., van Hattem, S., Schuttelaar, M. L. A., Gaastra, M. T. W., Kuijpers, D., … Nijsten, T. (2015). Patient Perception of Imiquimod Treatment for Actinic Keratosis and Superficial Basal Cell Carcinoma in 202 Patients. Dermatology: international journal for clinical and investigative dermatology, 231(1), 56–62. doi:10.1159/000381420 |