Up to this day, despite general improvements in safety precautions in both private and work environments, peripheral nerve trauma still occurs. One can image that the prevalence of these trauma related nerve injuries will decrease slowly in the Western civilization, but remains stable in countries developing their economy in a fast pace and industries primary goals thus not focus on safety regulations issues. Nevertheless the prevalence ranging between 2.8 and 5 % of peripheral nerve trauma in all open wounds remains rather stable (IJkema-Paassen et al. Biomaterials 25:1583–92, 2004; Noble et al. J Trauma 45:116–22, 1998). That being said it is clear that nerve reconstruction is of vital importance in the trauma and reconstructive care.