2D/3D catheter-based registration for image guidance in TACE of liver tumors

Image fusion of liver 2D X-ray images and pre or peri-operative 3D reconstructions can add valuable contextual information during image guided interventions. Such image fusion requires 2D/3D registration. In abdominal interventions, such as TACE of liver tumors, the initial alignment may be invalidated by e.g. breathing motion. We present a method that maintains the alignment between 3D Rotational Angiography (3DRA) and 2D X-ray, using the catheter position. To this end, we use the catheter in the 2D X-ray and the blood vessels in the 3DRA, then fuse 2D/3D using the knowledge that the catheter is inside the vessels. The registration is performed in two steps: First, we use a shape constraint to determine the most likely catheter positions inside the blood vessel tree. Next, we perform a rigid registration and take the best transformation over all previous selected catheter positions. The method is evaluated on phantom, clinical and simulated data.

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