Severe fatigue based on anaemia in patients with hidradenitis suppurativa: Report of two cases and a review of the literature

Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease. Patients often report fatigue, which is generally attributed to the debilitating psychosocial impact of HS. However, sometimes severe anaemia causes the fatigue. The co-occurrence of HS and anaemia is mentioned in reviews on the disease, but they refer to a single case series from 1968. Since, no studies have been published on this subject. Therefore, we present two representative cases of severe HS with fatigue, based on chronic marked anaemia. [...]