Central precocious puberty in girls is defined as the premature awakening of the nervous system resulting in the clinical onset of puberty before 8 years. Essential elements include breast development, growth acceleration and bone age progression. Treatment consists of administration of a gonadotropin-releasing hormone agonist. In this article the clinical picture, diagnosis and treatment are summarized.

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doi.org/10.1016/B978-0-12-801238-3.03912-X, hdl.handle.net/1765/84385
Erasmus MC: University Medical Center Rotterdam

Mul, D., Oostdijk, W., & Drop, S. (2014). Precocious Puberty, Central (Female). doi:10.1016/B978-0-12-801238-3.03912-X