A 56-year old man presented with a 9-month history of an erythematous, verrucous, keratotic lesion on his left hand. The clinical atypical lesion was excised and histopathological examination showed a well-differentiated squamous cell carcinoma. HPV-testing demonstrated positivity for HPV-16. UV-damage, trauma and smoking are possible explanations for the development of a squamous cell carcinoma. Further research examining the influence of HPV-infection and the development of cutaneous squamous cell carcinoma is required.

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Keywords HPV, HPV-16, Spinocellular carcinoma, Verruca
Persistent URL hdl.handle.net/1765/84463
Journal Nederlands Tijdschrift voor Dermatologie en Venereologie
Lanjouw, E, Koljenović, S, & de Waard-van der Spek, F.B. (2010). Growing skin defect on the back of the hand after chores. Nederlands Tijdschrift voor Dermatologie en Venereologie, 20(7), 394–397. Retrieved from http://hdl.handle.net/1765/84463