Oxytocin has been implicated in a variety of prosocial processes but most of this work has used laboratory tasks (such as the ultimatum game or the dictator game) to evaluate oxytocin's prosocial effects. In a double blind randomized trial we examined the influence of intranasal administration of oxytocin on real, high-cost donating money to a charity with-out any expectation for reciprocation. Participants in the current study were 57 female undergraduate students, aged 18-30 years, who received a nasal spray containing either 24 IU of oxytocin or a placebo, and were then given the opportunity to make a charita-ble donation. The participants reported how often their parents used love-withdrawal as a disciplinary strategy involving withholding love and affection after a failure or misbehavior. Oxytocin appeared to increase the participants' willingness to donate money to a charity but only in participants who experienced low levels of parental love-withdrawal. In contrast, oxytocin administration was ineffective in enhancing donating behavior in individuals who experienced high levels of parental love-withdrawal. We conclude that the positive effect of oxytocin administration on prosocial behavior may be limited to individuals with supportive backgrounds.

Donation, Intranasal administration, Love-withdrawal, Oxytocin, UNICEF
dx.doi.org/10.3389/fpsyg.2011.00258, hdl.handle.net/1765/84781
Frontiers in Psychology
Erasmus School of Social and Behavioural Sciences

van IJzendoorn, M.H, Huffmeijer, R, Alink, L.R.A, Bakermans-Kranenburg, M.J, & Tops, M. (2011). The impact of oxytocin administration on charitable donating is moderated by experiences of parental love-withdrawal. Frontiers in Psychology, 2(OCT). doi:10.3389/fpsyg.2011.00258